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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63586 | Zika virus-IN-1 | ||
Zika virus-IN-1 is an inhibitor of Zika virus (EC50: 1.56 μM). | |||
T61762 | Zika virus-IN-3 | ||
Zika virus-IN-3 (Compd 7) is a Zika virus inhibitor, with an EC 50 of 3.4 μM [1]. | |||
T81642 | NS2B-NS3pro-IN-1 | Virus Protease | |
NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1]. | |||
T63131 | ZIKV-IN-1 | ||
ZIKV-IN-1 is a potent inhibitor of zika virus (EC50: 2.8 μM, EC90: 6.8 μM). zIKV-IN-1 has anti-ZIKV effects and low cytotoxicity. zIKV-IN-1 shows high affinity for the RdRp domain of ZIKV. | |||
T81641 | NS2B-NS3pro-IN-2 | Virus Protease | |
Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1]. | |||
T63496 | CYP2C9/CYP2C19-IN-1 | ||
CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection. | |||
T63337 | CYP2C19-IN-1 | ||
CYP2C19-IN-1 is a potent, non-genotoxic, non-hepatotoxic inhibitor of CYP2C19. CYP2C19-IN-1 inhibits RNA-dependent RNA polymerase (RdRP) (Ki: 6.16 μM) and can be used to study Zika virus (ZIKV) infection. | |||
T70941 | CLR01 sodium | ||
CLR01 is a molecular tweezer. CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy. CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro ... | |||
T78618 | NSC 288387 | Virus Protease | |
NSC 288387, a pan-flavivirus MTase inhibitor, binds to the SAM-binding pocket and effectively inhibits Zika virus (ZIKV) with an IC50 of 0.2 μM, also preventing viral replication in cell culture [1]. | |||
T21978 | P-nitro-Pifithrin-α | ||
p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Mor... | |||
T80003 | Wulfenioidin H | ||
Wulfenioidin H (Compound 5), a diterpenoid, demonstrates anti-Zika virus (ZIKV) activity by inhibiting the expression of the ZIKV envelope (E) protein, resulting in an effective concentration \( EC_{50} \) value of 8.50 ... | |||
T80729 | ZIKV-IN-6 | ||
ZIKV-IN-6 (compound 22) acts as a direct inhibitor of the Zika virus (ZIKV) by binding to its RNA-dependent RNA polymerase (RdRp) and obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. This compound also d... |